Author: epilalis
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eNIOS was awarded the 1st prize of Pfizer’s accelerator Start4Health
eNIOS was awarded the 1st prize of Start4Health, an accelerator organized by Pfizer’s Center of Digital Innovation. Start4Health focused on Digital Health and targeted startup companies that develop solutions that can tackle challenges of the health industry, improve the digital experience of patients and promote wellness through technology. eNIOS worked…
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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer (Nature Communications)
Our new paper in Nature Communications, involving functional transcriptomic analysis with the e-NIOS BioInfoMiner platform. BioInfoMiner enables an automated data, but also biology-driven interpretation of omic data, making evident which are the crucial genes driving the phenotypes and how they are interacting. https://www.nature.com/articles/s41467-022-30159-0 Almanza A, Mnich K, Blomme A, Robinson…
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Integration of Raman spectra with transcriptome data in glioblastoma multiforme defines tumour subtypes and predicts patient outcome
Glioblastoma Multiforme is the most aggressive form of primary brain tumors. Raman spectroscopy is an imaging technique that has been applied to assess molecular compositions of living cells to characterize cell types and states. However, owing to the diverse molecular species in cells and challenges of assigning peaks to specific…
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Integration of Raman spectra with transcriptome data in glioblastoma multiforme defines tumour subtypes and predicts patient outcome
Glioblastoma Multiforme is the most aggressive form of primary brain tumors. Raman spectroscopy is an imaging technique that has been applied to assess molecular compositions of living cells to characterize cell types and states. However, owing to the diverse molecular species in cells and challenges of assigning peaks to specific…
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Epigenetics in Breast Cancer Therapy-New Strategies and Future Nanomedicine Perspectives
e-NIOS is a partner of the international INNOCENT project, with the aim to develop an innovative multifunctional nano-pharmaceutical to overcome the low efficacy and frequent relapses in breast cancer treatment. The use of nano-based delivery systems, together with the benefits of a new generation of epi-drugs and the emergence of…
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Announcement of BioS Online Seminars: Digital Skills on Computational Biology for Health Professionals, 15-16 October 2020
Within the framework of the Erasmus days, the BioS project offers further online seminars on modules 1 to 3 to deepen and apply the knowledge acquired in the course. We would like to invite you to join us. https://www.erasmusdays.eu/event/bios-project/ To participate in the BioS Online Seminar, please register under: https://docs.google.com/forms/d/e/1FAIpQLSfBTZyQs3pFRskynuEkocOzqzW_vc5TeTodxWDlG375VvrqDg/viewform…
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BioInfoMiner elucidates the role of the early secretory pathway in SARS-CoV-2 infection
https://doi.org/10.1083/jcb.202006005 Here, we analyze and discuss the contribution of the molecular machines operating in the early secretory pathway in the biogenesis of SARS-CoV-2 and their relevance for potential antiviral targeting. The fact that these molecular machines are conserved throughout evolution, together with the redundancy and tissue specificity of their components,…
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RA-map: a state-of-the-art interactive knowledge base for rheumatoid arthritis
RA-map is a fully annotated, expert validated, state-of-the-art knowledge base for RA in the form of a molecular map. BioInfoMiner was used for topological, functional and pharmacogenomic analysis. The publication is accessible at: Vidisha Singh, George D Kalliolias, Marek Ostaszewski, Maëva Veyssiere, Eleftherios Pilalis, Piotr Gawron, Alexander Mazein, Eric Bonnet,…