BioInfoMiner

Intelligent, automated interpretation of genomic data

https://bioinfominer.com

BioInfoMiner delivers unsupervized, fast and integrative interpretation of -omics experiments. The tool performs prioritization of key processes and derives a compact signature, consisting of systemic processes and their driver genes.

Key aspects of BioInfoMiner:

  • Interpetation vs description. BioInfoMiner does not perform similarly to typical enrichment analyses, which yield a huge population of bulk, descriptive terms, of no further utility
  • Integration vs aggregation.BioInfoMiner does not perform as an aggregator, simply collecting and presenting bulk annotations from numerous public databases
  • Derives a small, concise functional interpretation of the investigated phenotype
  • Derives a small set of robust, actionable biomarkers, strong candidates for targeting and/or using as discriminators

The derived signature constitutes a deconvoluted projection onto biological knowledge networks, corrected for biases and inconsistencies. Thus, it serves as a rational basis for unsupervised and systematic comparison between different physiological conditions.

signature

 

Selected publications involving BioInfoMiner

Features:

  • Fast, unsupervised interpretation suitable for streamlined processes
  • Integrates multiple layers of biological regulation (genomic/epigenomic, structural/functional)
  • Unique, proprietary algorithm for knowledge extraction that observes and corrects not only technical, but also biological noise
  • Delivers signatures of molecular biomarkers, characterized by minimum size/maximum information
  • Works with a variety of organisms of all Kingdoms

Applications:

  • Design of CRISPR targeting strategies
  • Precision medicine
  • Pharmacogenomics
  • Drug discovery
  • Diagnostics, Prognostics, Monitoring
  • Biotechnology