eNIOS computational platform streamlines data-driven identification of sets of impactful, discriminatory genetic variants.
Personalized signatures give direct insights into the molecular networks underlying complex phenotypes and restrain considerably the space of candidate impactful variants.
Common variant detection applications do not really take into account the personal genetic variation and rely solely on sparse reports of clinical significance from public databases. eNIOS VCF analyzer, in contrast, also detects the cumulative impact of combinations of variants, even of those with previously unknown clinical significance. This approach brings precision medicine applications into a whole new personalized level, where individual genetic idiosyncrasy does count.